Protein Details: Gap junction beta-2 protein

Protein ID

ICDB_Pro_0734

Protein Name

Gap junction beta-2 protein

Gene Name

Gjb2; Cxn-26

Organism

Mus musculus (Mouse)

Length

226 amino acids

AlphaFoldDB

AF-Q00977-F1-model_v4.pdb

Function

Sequence

MDWGTLQSILGGVNKHSTSIGKIWLTVLFIFRIMILVVAAKEVWGDEQADFVCNTLQPGCKNVCYDHHFPISHIRLWALQLIMVSTPALLVAMHVAYRRHEKKRKFMKGEIKNEFKDIEEIKTQKVRIEGSLWWTYTTSIFFRVIFEAVFMYVFYIMYNGFFMQRLVKCNAWPCPNTVDCFISRPTEKTVFTVFMISVSGICILLNITELCYLFVRYCSGKSKRPV

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

Detected in cochlea (at protein level) (PubMed:15692151). Detected in cochlea . Liver; kidney; intestine; lung; spleen; stomach; testis and brain; but not heart and adult skeletal muscle. Liver; kidney; intestine; lung; spleen; stomach; testis and brain; but not heart and adult skeletal muscle. Liver; kidney; intestine; lung; spleen; stomach; testis and brain; but not heart and adult skeletal muscle.

DOI ID

10.1016/0012-1606(91)90452-9; 10.1101/gr.2596504; 10.1152/ajpcell.00341.2004; 10.1093/hmg/ddp490

RefSeq

NP_032151.1